Hepatic myelopathy is a rare neurological complication of liver cirrhosis, that involves spastic paraplegia caused by lateral cord demyelinisation especially due to accumulation of some metabolites such as ammonia and manganese. We report a young adult woman presenting with spasticity and paraparesia in extremities after TIPS application and undergone to deceased liver transplantation. 39 year old woman underwent deceased liver transplantation cause of cyriptogenic liver cirrhosis. She underwent TIPS procedure 5 years ago. After that, hepathic encephalopathy and spasticity appeared. She waited in waiting list for 3 years. Neurological findings after liver transplantation significantly decreased, but did not return to normal. Hepatic myelopathy is very rare. LT can provide improvement in neurologic findings. After the emerge of neurological findings, the earlier LT, the better clinical to return to normal.