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A case report of reversible intracranial lesions after long-term Azathioprine therapy in an autoimmune hepatitis patient
1Department of Gastroenterology, Hacettepe University School of Medicine, Ankara, Turkiye
2Department of Radiology, Hacettepe University School of Medicine, Ankara, Turkiye
Hepatology Forum 2023; 4(2): 78-81 DOI: 10.14744/hf.2023.2023.0006 PMCID: PMC10209979
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Abstract

This study is written to report a case of 67-year-old female with known au-toimmune hepatitis (AIH) who developed balance and walking difficulties. Clinical and imaging investigations were more suggestive of AIH suffering from lymphoproliferative disease. To identify the underlying suspected lym-phoproliferative disease, series of brain scans were performed, which showed multiple brain lesions. This is a report on a striking case of multiple contrast enhanced brain lesions discovered in an AIH patient that was resolved upon withdrawal of azathioprine. Many side effects of azathioprine are acknowl-edged around the world; however, to the very best of our knowledge, an article on azathioprine inducing suspected malignancy was never reported.